Mysimba should also be stopped if patients have not lost at least 5% of their initial body weight after 4 months of treatment.įor further information, see the package leaflet. Patients should have their response and tolerability to the medicine checked regularly and treatment should be stopped in patients who have certain side effects such as an increase in blood pressure. Treatment with Mysimba is started with a single tablet each morning, with the dose gradually increased over 4 weeks to the recommended dose of two tablets twice a day, preferably taken with food. Prolonged-release means that naltrexone and bupropion are released slowly from the tablet over a few hours. Mysimba is available as prolonged-release tablets containing 7.2 mg naltrexone and 78 mg bupropion and can only be obtained with a prescription. Mysimba contains the active substances naltrexone and bupropion, which are licensed individually in the EU for other uses.
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